The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically engineered variant of this enzyme leads to improved cold tolerance and enhanced phosphate uptake, improving yield in field trials.
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Randomly selecting border points or using simple geometric divisions (squares/hexagons) results in too many border points per cluster (50-80). This leads to a shortcut explosion (N*(N-1)/2 shortcuts), making the files large and and calculations slow.
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